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Structural Basis for Assembly of the Mn(IV)/Fe(III) Cofactor in the Class Ic Ribonucleotide Reductase from Chlamydia trachomatis
The class Ic ribonucleotide reductase (RNR) from Chlamydia trachomatis (Ct) employs a Mn(IV)/Fe(III) cofactor in each monomer of its β(2) subunit to initiate nucleotide reduction. The cofactor forms by reaction of Mn(II)/Fe(II)-β(2) with O(2). Previously, in vitro cofactor assembly from apo β(2) and...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3821933/ https://ncbi.nlm.nih.gov/pubmed/23924396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400819x |
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