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Evidence that the β Subunit of Chlamydia trachomatis Ribonucleotide Reductase is Active with the Manganese Ion of its Manganese(IV)/Iron(III) Cofactor in Site 1
The reaction of a class I ribonucleotide reductase (RNR) begins when a cofactor in the β subunit oxidizes a cysteine residue <35 Å away in the α subunit, generating a thiyl radical. In the class Ic enzyme from Chlamydia trachomatis (Ct), the cysteine oxidant is the Mn(IV) ion of a Mn(IV)/Fe(III)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297472/ https://ncbi.nlm.nih.gov/pubmed/22242660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211314p |
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