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Branched Activation- and Catalysis-Specific Pathways for Electron Relay to the Manganese/Iron Cofactor in Ribonucleotide Reductase from Chlamydia trachomatis
A conventional class I (subclass a or b) ribonucleotide reductase (RNR) employs a tyrosyl radical (Y(•)) in its R2 subunit for reversible generation of a 3′-hydrogen-abstracting cysteine radical in its R1 subunit by proton-coupled electron transfer (PCET) through a network of aromatic amino acids sp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681183/ https://ncbi.nlm.nih.gov/pubmed/18656954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800881m |
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