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Histone Deacetylase Inhibition Downregulates Collagen 3A1 in Fibrotic Lung Fibroblasts

Idiopathic pulmonary fibrosis (IPF) is a deadly disease characterized by chronic inflammation and excessive collagen accumulation in the lung. Myofibroblasts are the primary collagen-producing cells in pulmonary fibrosis. Histone deacetylase inhibitor (HDACi) can affect gene expression, and some, su...

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Detalhes bibliográficos
Main Authors: Zhang, Xiangyu, Liu, Hui, Hock, Thomas, Thannickal, Victor J., Sanders, Yan Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821575/
https://ncbi.nlm.nih.gov/pubmed/24084714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms141019605
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