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Epigenetic Regulation of Thy-1 by Histone Deacetylase Inhibitor in Rat Lung Fibroblasts
Thy-1 is a cell surface glycoprotein present on normal lung fibroblasts but absent from the fibroblastic foci of idiopathic pulmonary fibrosis. Thy-1 correlates inversely with fibrogenic phenotypic characteristics and functions as a “fibrosis suppressor.” Promoter region hypermethylation can silence...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Thoracic Society
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145068/ https://ncbi.nlm.nih.gov/pubmed/20724553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0154OC |
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