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Thy-1 Promoter Hypermethylation: A Novel Epigenetic Pathogenic Mechanism in Pulmonary Fibrosis

Mechanisms regulating myofibroblastic differentiation of fibroblasts within fibroblastic foci in idiopathic pulmonary fibrosis (IPF) remain unclear. Epigenetic processes, including DNA methylation, produce heritable but potentially reversible changes in DNA or its associated proteins and are promine...

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Библиографические подробности
Главные авторы: Sanders, Yan Y., Pardo, Annie, Selman, Moisés, Nuovo, Gerard J., Tollefsbol, Trygve O., Siegal, Gene P., Hagood, James S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574530/
https://ncbi.nlm.nih.gov/pubmed/18556592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0322OC
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