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Thy-1 Promoter Hypermethylation: A Novel Epigenetic Pathogenic Mechanism in Pulmonary Fibrosis

Mechanisms regulating myofibroblastic differentiation of fibroblasts within fibroblastic foci in idiopathic pulmonary fibrosis (IPF) remain unclear. Epigenetic processes, including DNA methylation, produce heritable but potentially reversible changes in DNA or its associated proteins and are promine...

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Hlavní autoři: Sanders, Yan Y., Pardo, Annie, Selman, Moisés, Nuovo, Gerard J., Tollefsbol, Trygve O., Siegal, Gene P., Hagood, James S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574530/
https://ncbi.nlm.nih.gov/pubmed/18556592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0322OC
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