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Epigenetic Regulation of Caveolin-1 Gene Expression in Lung Fibroblasts

Fibrotic disorders are associated with tissue accumulation of fibroblasts. We recently showed that caveolin (Cav)-1 gene suppression by a profibrotic cytokine, transforming growth factor (TGF)-β1, contributes to fibroblast proliferation and apoptosis resistance. Cav-1 has been shown to be constituti...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Sanders, Yan Y., Liu, Hui, Scruggs, Anne M., Duncan, Steven R., Huang, Steven K., Thannickal, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248956/
https://ncbi.nlm.nih.gov/pubmed/27560128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0034OC
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