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Liver-specific Cholesteryl Ester Hydrolase deficiency attenuates sterol elimination in the feces and increases Atherosclerosis in Ldlr-/- Mice
OBJECTIVE: Liver is the major organ responsible for the final elimination of cholesterol from the body either as biliary cholesterol or as bile acids. Intracellular hydrolysis of lipoprotein-derived cholesteryl esters (CE) is essential to generate the free cholesterol (FC) required for this process....
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3819806/ https://ncbi.nlm.nih.gov/pubmed/23744992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301634 |
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