Improved Insulin Sensitivity in High Fat- and High Cholesterol-fed Ldlr(−/−) Mice with Macrophage-specific Transgenic Expression of Cholesteryl Ester Hydrolase: ROLE OF MACROPHAGE INFLAMMATION AND INFILTRATION INTO ADIPOSE TISSUE

Cellular cholesterol balance induces changes in the inflammatory status of macrophages, and low grade chronic inflammation is increasingly being recognized as one of the key steps in the development of atherosclerosis as well as insulin resistance. Cholesteryl ester hydrolase (CEH) catalyzes the hyd...

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Bibliographic Details
Main Authors: Bie, Jinghua, Zhao, Bin, Song, Jingmei, Ghosh, Shobha
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859525/
https://ncbi.nlm.nih.gov/pubmed/20189995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069781
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