Improved Insulin Sensitivity in High Fat- and High Cholesterol-fed Ldlr(−/−) Mice with Macrophage-specific Transgenic Expression of Cholesteryl Ester Hydrolase: ROLE OF MACROPHAGE INFLAMMATION AND INFILTRATION INTO ADIPOSE TISSUE

Cellular cholesterol balance induces changes in the inflammatory status of macrophages, and low grade chronic inflammation is increasingly being recognized as one of the key steps in the development of atherosclerosis as well as insulin resistance. Cholesteryl ester hydrolase (CEH) catalyzes the hyd...

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Hlavní autoři: Bie, Jinghua, Zhao, Bin, Song, Jingmei, Ghosh, Shobha
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859525/
https://ncbi.nlm.nih.gov/pubmed/20189995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069781
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