Improved Insulin Sensitivity in High Fat- and High Cholesterol-fed Ldlr(−/−) Mice with Macrophage-specific Transgenic Expression of Cholesteryl Ester Hydrolase: ROLE OF MACROPHAGE INFLAMMATION AND INFILTRATION INTO ADIPOSE TISSUE

Cellular cholesterol balance induces changes in the inflammatory status of macrophages, and low grade chronic inflammation is increasingly being recognized as one of the key steps in the development of atherosclerosis as well as insulin resistance. Cholesteryl ester hydrolase (CEH) catalyzes the hyd...

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Autores principales: Bie, Jinghua, Zhao, Bin, Song, Jingmei, Ghosh, Shobha
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859525/
https://ncbi.nlm.nih.gov/pubmed/20189995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069781
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