ABCG2 is not able to catalyze glutathione efflux and does not contribute to GSH-dependent collateral sensitivity

ABCG2 is a key human ATP-binding cassette (ABC) transporter mediating cancer cell chemoresistance. In the case of ABCC1, another multidrug transporter, earlier findings documented that certain modulators greatly increase ABCC1-mediated glutathione (GSH) efflux and, upon depletion of intracellular GS...

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Detalhes bibliográficos
Main Authors: Gauthier, Charlotte, Ozvegy-Laczka, Csilla, Szakacs, Gergely, Sarkadi, Balazs, Di Pietro, Attilio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819521/
https://ncbi.nlm.nih.gov/pubmed/24312054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00138
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