Arginine 383 is a crucial residue in ABCG2 biogenesis

ABCG2 is an ATP-binding cassette half-transporter initially identified in multidrug-resistant cancer cell lines and recently suggested to play an important role in pharmacokinetics. Here we report studies of a conserved arginine predicted to localize near the cytoplasmic side of TM1. First, we deter...

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Detalhes bibliográficos
Main Authors: Polgar, Orsolya, Ediriwickrema, Lilangi S., Robey, Robert W., Sharma, Ajay, Hegde, Ramanujan S., Li, Yongfu, Xia, Di, Ward, Yvona, Dean, Michael, Ozvegy-Laczka, Csilla, Sarkadi, Balazs, Bates, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163909/
https://ncbi.nlm.nih.gov/pubmed/19406100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.04.016
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