Mutational Studies of G553 in TM5 of ABCG2: a Residue Potentially Involved in Dimerization

ABCG2 is an ATP-binding cassette half-transporter conferring resistance to chemotherapeutic agents such as mitoxantrone, irinotecan, and flavopiridol. With its one transmembrane and one ATP-binding domain, ABCG2 is thought to homodimerize for function. One conserved region potentially involved in di...

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Autori principali: Polgar, Orsolya, Ozvegy-Laczka, Csilla, Robey, Robert W., Morisaki, Kuniaki, Okada, Masaki, Tamaki, Akina, Koblos, Gabriella, Elkind, N. Barry, Ward, Yvona, Dean, Michael, Sarkadi, Balazs, Bates, Susan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548280/
https://ncbi.nlm.nih.gov/pubmed/16618113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0521590
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