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Mutational Studies of G553 in TM5 of ABCG2: a Residue Potentially Involved in Dimerization
ABCG2 is an ATP-binding cassette half-transporter conferring resistance to chemotherapeutic agents such as mitoxantrone, irinotecan, and flavopiridol. With its one transmembrane and one ATP-binding domain, ABCG2 is thought to homodimerize for function. One conserved region potentially involved in di...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2548280/ https://ncbi.nlm.nih.gov/pubmed/16618113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0521590 |
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