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Kinetic Analysis Reveals Differences in the Binding Mechanism of Calmodulin and Calmodulin-like Protein to the IQ Motifs of Myosin-10()

Myo10 is an unconventional myosin with important functions in filopodial motility, cell migration, and cell adhesion. The neck region of Myo10 contains three IQ motifs that bind calmodulin (CaM) or the tissue-restricted calmodulin-like protein (CLP) as light chains. However, little is known about th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Caride, Ariel J., Bennett, Richard D., Strehler, Emanuel E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818122/
https://ncbi.nlm.nih.gov/pubmed/20731332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100644q
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