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THE PLASMA MEMBRANE CA(2+) PUMP ISOFORM 4A DIFFERS FROM ISOFORM 4B IN THE MECHANISM OF CALMODULIN BINDING AND ACTIVATION KINETICS. IMPLICATIONS FOR CA(2+) SIGNALING

The inhibition by the regulatory domain and the interaction with calmodulin (CaM) vary among plasma membrane calcium pump (PMCA) isoforms. To explore these differences, the kinetics of CaM effects on PMCA4a were investigated and compared with those of PMCA4b. The maximal apparent rate constant for C...

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Bibliografske podrobnosti
Main Authors: Caride, Ariel J., Filoteo, Adelaida G., Penniston, John T., Strehler, Emanuel E.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680277/
https://ncbi.nlm.nih.gov/pubmed/17595168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701129200
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