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THE PLASMA MEMBRANE CA(2+) PUMP ISOFORM 4A DIFFERS FROM ISOFORM 4B IN THE MECHANISM OF CALMODULIN BINDING AND ACTIVATION KINETICS. IMPLICATIONS FOR CA(2+) SIGNALING
The inhibition by the regulatory domain and the interaction with calmodulin (CaM) vary among plasma membrane calcium pump (PMCA) isoforms. To explore these differences, the kinetics of CaM effects on PMCA4a were investigated and compared with those of PMCA4b. The maximal apparent rate constant for C...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680277/ https://ncbi.nlm.nih.gov/pubmed/17595168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701129200 |
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