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Alternative Pathways for Association and Dissociation of the Calmodulin-binding Domain of Plasma Membrane Ca(2+)-ATPase Isoform 4b (PMCA4b)
The calmodulin (CaM)-binding domain of isoform 4b of the plasma membrane Ca(2+) -ATPase (PMCA) pump is represented by peptide C28. CaM binds to either PMCA or C28 by a mechanism in which the primary anchor residue Trp-1093 binds to the C-terminal lobe of the extended CaM molecule, followed by collap...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436155/ https://ncbi.nlm.nih.gov/pubmed/22767601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377556 |
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