Calmodulin Wraps around Its Binding Domain in the Plasma Membrane Ca(2+) Pump Anchored by a Novel 18-1 Motif

Using solution NMR spectroscopy, we obtained the structure of Ca(2+)-calmodulin (holoCaM) in complex with peptide C28 from the binding domain of the plasma membrane Ca(2+)-ATPase (PMCA) pump isoform 4b. This provides the first atomic resolution insight into the binding mode of holoCaM to the full-le...

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Detalhes bibliográficos
Main Authors: Juranic, Nenad, Atanasova, Elena, Filoteo, Adelaida G., Macura, Slobodan, Prendergast, Franklyn G., Penniston, John T., Strehler, Emanuel E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823543/
https://ncbi.nlm.nih.gov/pubmed/19996092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060491
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