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Kinetic Analysis Reveals Differences in the Binding Mechanism of Calmodulin and Calmodulin-like Protein to the IQ Motifs of Myosin-10()

Myo10 is an unconventional myosin with important functions in filopodial motility, cell migration, and cell adhesion. The neck region of Myo10 contains three IQ motifs that bind calmodulin (CaM) or the tissue-restricted calmodulin-like protein (CLP) as light chains. However, little is known about th...

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Bibliografiske detaljer
Main Authors: Caride, Ariel J., Bennett, Richard D., Strehler, Emanuel E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818122/
https://ncbi.nlm.nih.gov/pubmed/20731332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100644q
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