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Kinetic Analysis Reveals Differences in the Binding Mechanism of Calmodulin and Calmodulin-like Protein to the IQ Motifs of Myosin-10()

Myo10 is an unconventional myosin with important functions in filopodial motility, cell migration, and cell adhesion. The neck region of Myo10 contains three IQ motifs that bind calmodulin (CaM) or the tissue-restricted calmodulin-like protein (CLP) as light chains. However, little is known about th...

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Bibliographic Details
Main Authors: Caride, Ariel J., Bennett, Richard D., Strehler, Emanuel E.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818122/
https://ncbi.nlm.nih.gov/pubmed/20731332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100644q
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