SENP1 deSUMOylates and regulates Pin1 protein activity and cellular function

The Pin1 prolyl isomerase regulates phosphorylation signaling by controlling protein conformation after phosphorylation and its upregulation promotes oncogenesis via acting on numerous oncogenic molecules. SUMOylation and deSUMOylation are dynamic mechanisms regulating a spectrum of protein activiti...

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Autors principals: Chen, Chun-Hau, Chang, Che-Chang, Lee, Tae Ho, Luo, ManLi, Huang, Pengyu, Liao, Pei-Hsin, Wei, Shuo, Li, Fu-An, Chen, Ruey-Hwa, Zhou, Xiao Zhen, Shih, Hsiu-Ming, Lu, Kun Ping
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818121/
https://ncbi.nlm.nih.gov/pubmed/23633483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4360
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