SENP1 deSUMOylates and regulates Pin1 protein activity and cellular function

The Pin1 prolyl isomerase regulates phosphorylation signaling by controlling protein conformation after phosphorylation and its upregulation promotes oncogenesis via acting on numerous oncogenic molecules. SUMOylation and deSUMOylation are dynamic mechanisms regulating a spectrum of protein activiti...

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Hlavní autoři: Chen, Chun-Hau, Chang, Che-Chang, Lee, Tae Ho, Luo, ManLi, Huang, Pengyu, Liao, Pei-Hsin, Wei, Shuo, Li, Fu-An, Chen, Ruey-Hwa, Zhou, Xiao Zhen, Shih, Hsiu-Ming, Lu, Kun Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818121/
https://ncbi.nlm.nih.gov/pubmed/23633483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4360
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