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The CD8(+)HLA-DR(+) T cells expanded in HIV-1 infection are qualitatively identical to those from healthy controls

HIV-induced immune activation leads to expansion of a subset of human CD8(+) T cells expressing HLA-DR antigens. Expansion of CD8(+)HLA-DR(+) T cells can be also observed in non-HIV settings including several autoimmune diseases and aging. Although these cells are felt to represent “immune exhaustio...

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Hlavní autoři: Imamichi, Hiromi, Lempicki, Richard A., Adelsberger, Joseph W., Hasley, Rebecca B., Rosenberg, Alice, Roby, Gregg, Rehm, Catherine A., Nelson, Amy, Krishnan, Sonya, Pavlick, Mark, Woods, Christian J., Baseler, Michael W., Lane, H. Clifford
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818066/
https://ncbi.nlm.nih.gov/pubmed/22777759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142046
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