HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells

HIV infection is characterized by a brisk immune activation that plays an important role in the CD4 depletion and immune dysfunction of patients with AIDS. The mechanism underlying this activation is poorly understood. In the current study, we tested the hypothesis that this activation is the net pr...

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Hlavní autoři: Catalfamo, Marta, Di Mascio, Michele, Hu, Zonghui, Srinivasula, Sharat, Thaker, Vishakha, Adelsberger, Joseph, Rupert, Adam, Baseler, Michael, Tagaya, Yutaka, Roby, Gregg, Rehm, Catherine, Follmann, Dean, Lane, H. Clifford
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596741/
https://ncbi.nlm.nih.gov/pubmed/19060209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810032105
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