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HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells

HIV infection is characterized by a brisk immune activation that plays an important role in the CD4 depletion and immune dysfunction of patients with AIDS. The mechanism underlying this activation is poorly understood. In the current study, we tested the hypothesis that this activation is the net pr...

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書誌詳細
主要な著者: Catalfamo, Marta, Di Mascio, Michele, Hu, Zonghui, Srinivasula, Sharat, Thaker, Vishakha, Adelsberger, Joseph, Rupert, Adam, Baseler, Michael, Tagaya, Yutaka, Roby, Gregg, Rehm, Catherine, Follmann, Dean, Lane, H. Clifford
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596741/
https://ncbi.nlm.nih.gov/pubmed/19060209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810032105
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