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The CD8(+)HLA-DR(+) T cells expanded in HIV-1 infection are qualitatively identical to those from healthy controls

HIV-induced immune activation leads to expansion of a subset of human CD8(+) T cells expressing HLA-DR antigens. Expansion of CD8(+)HLA-DR(+) T cells can be also observed in non-HIV settings including several autoimmune diseases and aging. Although these cells are felt to represent “immune exhaustio...

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Detalhes bibliográficos
Main Authors: Imamichi, Hiromi, Lempicki, Richard A., Adelsberger, Joseph W., Hasley, Rebecca B., Rosenberg, Alice, Roby, Gregg, Rehm, Catherine A., Nelson, Amy, Krishnan, Sonya, Pavlick, Mark, Woods, Christian J., Baseler, Michael W., Lane, H. Clifford
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818066/
https://ncbi.nlm.nih.gov/pubmed/22777759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142046
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