CD4 and CD8 T Cell Immune Activation during Chronic HIV Infection: Roles of Homeostasis, HIV, Type I IFN, and IL-7

Immune activation plays an important role in the pathogenesis of HIV disease. Although the causes are not fully understood, the forces that lead to immune dysfunction differ for CD4 and CD8 T cells. In this study, we report that the molecular pathways that drive immune activation during chronic HIV...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Catalfamo, Marta, Wilhelm, Christopher, Tcheung, Lueng, Proschan, Michael, Friesen, Travis, Park, Jung-Hyun, Adelsberger, Joseph, Baseler, Michael, Maldarelli, Frank, Davey, Richard, Roby, Gregg, Rehm, Catherine, Lane, Clifford
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394280/
https://ncbi.nlm.nih.gov/pubmed/21257970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002000
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