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Sigma-2 receptor ligand as a novel method for delivering a SMAC mimetic drug for treating ovarian cancer
BACKGROUND: The sigma-2 receptor has been validated as a biomarker for proliferating tumours. Second mitochondria-derived activator of caspase (Smac) is a protein released from mitochondria into the cytosol, leading to apoptosis. In this study, we investigated a sigma-2 ligand as a tumour-targeting...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817331/ https://ncbi.nlm.nih.gov/pubmed/24104966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.593 |
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