Evolutionary etiology of high-grade astrocytomas

Glioblastoma (GBM), the most common brain malignancy, remains fatal with no effective treatment. Analyses of common aberrations in GBM suggest major regulatory pathways associated with disease etiology. However, 90% of GBMs are diagnosed at an advanced stage (primary GBMs), providing no access to ea...

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Bibliographic Details
Main Authors: Song, Yurong, Zhang, Qian, Kutlu, Burak, Difilippantonio, Simone, Bash, Ryan, Gilbert, Debra, Yin, Chaoying, O’Sullivan, T. Norene, Yang, Chunyu, Kozlov, Serguei, Bullitt, Elizabeth, McCarthy, Ken D., Kafri, Tal, Louis, David N., Miller, C. Ryan, Hood, Leroy, Van Dyke, Terry
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816471/
https://ncbi.nlm.nih.gov/pubmed/24114272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317026110
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