Evolutionary etiology of high-grade astrocytomas

Glioblastoma (GBM), the most common brain malignancy, remains fatal with no effective treatment. Analyses of common aberrations in GBM suggest major regulatory pathways associated with disease etiology. However, 90% of GBMs are diagnosed at an advanced stage (primary GBMs), providing no access to ea...

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Autori principali: Song, Yurong, Zhang, Qian, Kutlu, Burak, Difilippantonio, Simone, Bash, Ryan, Gilbert, Debra, Yin, Chaoying, O’Sullivan, T. Norene, Yang, Chunyu, Kozlov, Serguei, Bullitt, Elizabeth, McCarthy, Ken D., Kafri, Tal, Louis, David N., Miller, C. Ryan, Hood, Leroy, Van Dyke, Terry
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816471/
https://ncbi.nlm.nih.gov/pubmed/24114272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317026110
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