Carcinoma Initiation via Rb Tumor Suppressor Inactivation: A Versatile Approach to Epithelial Subtype-Dependent Cancer Initiation in Diverse Tissues

Carcinomas arise in a complex microenvironment consisting of multiple distinct epithelial lineages surrounded by a variety of stromal cell types. Understanding cancer etiologies requires evaluating the relationship among cell types during disease initiation and through progression. Genetically engin...

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Autors principals: Song, Yurong, Gilbert, Debra, O’Sullivan, T. Norene, Yang, Chunyu, Pan, Wenqi, Fathalizadeh, Alisan, Lu, Lucy, Haines, Diana C., Martin, Philip L., Van Dyke, Terry
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846618/
https://ncbi.nlm.nih.gov/pubmed/24312475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080459
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