Enhancing the Function of CD34(+) Cells by Targeting Plasminogen Activator Inhibitor-1

Previously, we showed that transient inhibition of TGF- β1 resulted in correction of key aspects of diabetes-induced CD34(+) cell dysfunction. In this report, we examine the effect of transient inhibition of plasminogen activator inhibitor-1 (PAI-1), a major gene target of TGF-β1 activation. Using g...

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Bibliographic Details
Main Authors: Hazra, Sugata, Stepps, Valerie, Bhatwadekar, Ashay D., Caballero, Sergio, Boulton, Michael E., Higgins, Paul J., Nikonova, Elena V., Pepine, Carl J., Thut, Catherine, Finney, Eva M., Stone, David J., Bartelmez, Stephen H., Grant, Maria B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815099/
https://ncbi.nlm.nih.gov/pubmed/24223881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079067
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