Transient Inhibition of Transforming Growth Factor-β1 in Human Diabetic CD34(+) Cells Enhances Vascular Reparative Functions

OBJECTIVE: Peripheral blood CD34(+) cells from diabetic patients demonstrate reduced vascular reparative function due to decreased proliferation and diminished migratory prowess, largely resulting from decreased nitric oxide (NO) bioavailability. The level of TGF-β, a key factor that modulates stem...

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Detalhes bibliográficos
Main Authors: Bhatwadekar, Ashay D., Guerin, E.P., Jarajapu, Yagna P.R., Caballero, Sergio, Sheridan, Carl, Kent, David, Kennedy, Laurence, Lansang, M. Cecilia, Ruscetti, Frank W., Pepine, Carl J., Higgins, Paul J., Bartelmez, Stephen H., Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911069/
https://ncbi.nlm.nih.gov/pubmed/20460428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0287
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