Enhancing the Function of CD34(+) Cells by Targeting Plasminogen Activator Inhibitor-1

Previously, we showed that transient inhibition of TGF- β1 resulted in correction of key aspects of diabetes-induced CD34(+) cell dysfunction. In this report, we examine the effect of transient inhibition of plasminogen activator inhibitor-1 (PAI-1), a major gene target of TGF-β1 activation. Using g...

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Autors principals: Hazra, Sugata, Stepps, Valerie, Bhatwadekar, Ashay D., Caballero, Sergio, Boulton, Michael E., Higgins, Paul J., Nikonova, Elena V., Pepine, Carl J., Thut, Catherine, Finney, Eva M., Stone, David J., Bartelmez, Stephen H., Grant, Maria B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815099/
https://ncbi.nlm.nih.gov/pubmed/24223881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079067
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