miR-92a Corrects CD34(+) Cell Dysfunction in Diabetes by Modulating Core Circadian Genes Involved in Progenitor Differentiation

Autologous CD34(+) cells are widely used for vascular repair; however, in individuals with diabetes and microvascular disease these cells are dysfunctional. In this study, we examine expression of the clock genes Clock, Bmal, Per1, Per2, Cry1, and Cry2 in CD34(+) cells of diabetic and nondiabetic or...

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Bibliographische Detailangaben
Veröffentlicht in:Diabetes
Hauptverfasser: Bhatwadekar, Ashay D., Yan, Yuanqing, Stepps, Valerie, Hazra, Sugata, Korah, Maria, Bartelmez, Stephen, Chaqour, Brahim, Grant, Maria B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2015
Schlagworte:
Complications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876760/
https://ncbi.nlm.nih.gov/pubmed/26283734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0521
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