Activation of the ACE2/Angiotensin-(1–7)/Mas Receptor Axis Enhances the Reparative Function of Dysfunctional Diabetic Endothelial Progenitors

We tested the hypothesis that activation of the protective arm of the renin angiotensin system, the angiotensin-converting enzyme 2 (ACE2)/angiotensin-(1-7) [Ang-(1-7)]/Mas receptor axis, corrects the vasoreparative dysfunction typically seen in the CD34(+) cells isolated from diabetic individuals....

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Bibliographische Detailangaben
Hauptverfasser: Jarajapu, Yagna P.R., Bhatwadekar, Ashay D., Caballero, Sergio, Hazra, Sugata, Shenoy, Vinayak, Medina, Reinhold, Kent, David, Stitt, Alan W., Thut, Catherine, Finney, Eva M., Raizada, Mohan K., Grant, Maria B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2013
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609564/
https://ncbi.nlm.nih.gov/pubmed/23230080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0808
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