Transient Inhibition of Transforming Growth Factor-β1 in Human Diabetic CD34(+) Cells Enhances Vascular Reparative Functions

OBJECTIVE: Peripheral blood CD34(+) cells from diabetic patients demonstrate reduced vascular reparative function due to decreased proliferation and diminished migratory prowess, largely resulting from decreased nitric oxide (NO) bioavailability. The level of TGF-β, a key factor that modulates stem...

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Main Authors: Bhatwadekar, Ashay D., Guerin, E.P., Jarajapu, Yagna P.R., Caballero, Sergio, Sheridan, Carl, Kent, David, Kennedy, Laurence, Lansang, M. Cecilia, Ruscetti, Frank W., Pepine, Carl J., Higgins, Paul J., Bartelmez, Stephen H., Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2010
Assuntos:
Complications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911069/
https://ncbi.nlm.nih.gov/pubmed/20460428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0287
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