Chargement en cours...
P-glycoprotein Mediates Drug Resistance via a Novel Mechanism Involving Lysosomal Sequestration
Localization of the drug transporter P-glycoprotein (Pgp) to the plasma membrane is thought to be the only contributor of Pgp-mediated multidrug resistance (MDR). However, very little work has focused on the contribution of Pgp expressed in intracellular organelles to drug resistance. This investiga...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2013
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814770/ https://ncbi.nlm.nih.gov/pubmed/24062304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514091 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|