Di-2-pyridylketone 4,4-Dimethyl-3-thiosemicarbazone (Dp44mT) Overcomes Multidrug Resistance by a Novel Mechanism Involving the Hijacking of Lysosomal P-Glycoprotein (Pgp)

Lignende værker

• The Anticancer Agent Di-2-pyridylketone 4,4-Dimethyl-3-thiosemicarbazone (Dp44mT) Overcomes Prosurvival Autophagy by Two Mechanisms: PERSISTENT INDUCTION OF AUTOPHAGOSOME SYNTHESIS AND IMPAIRMENT OF LYSOSOMAL INTEGRITY
  af: Gutierrez, Elaine, et al.
  Udgivet: (2014)
• The novel thiosemicarbazone, di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone (DpC), inhibits neuroblastoma growth in vitro and in vivo via multiple mechanisms
  af: Guo, Zhu-Ling, et al.
  Udgivet: (2016)
• A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC
  af: Seebacher, Nicole A, et al.
  Udgivet: (2016)
• P-glycoprotein Mediates Drug Resistance via a Novel Mechanism Involving Lysosomal Sequestration
  af: Yamagishi, Tetsuo, et al.
  Udgivet: (2013)
• The redox-active, anti-cancer drug Dp44mT inhibits T-cell activation and CD25 through a copper-dependent mechanism
  af: Kalinowski, Danuta S., et al.
  Udgivet: (2013)