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Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

The dynamic modification of proteins by O-linked N-acetylglucosamine (O-GlcNAc) is an essential posttranslational modification present in higher eukaryotes. Removal of O-GlcNAc is catalysed by O-GlcNAcase, a multi-domain enzyme that has been reported to be bifunctional, possessing both glycoside hyd...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rao, Francesco V., Schüttelkopf, Alexander W., Dorfmueller, Helge C., Ferenbach, Andrew T., Navratilova, Iva, van Aalten, Daan M. F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Royal Society 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814719/
https://ncbi.nlm.nih.gov/pubmed/24088714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.130021
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