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Slow conformational changes in MutS and DNA direct ordered transitions between mismatch search, recognition and signaling of DNA repair

MutS functions in mismatch repair (MMR) to scan DNA for errors, identify a target site and trigger subsequent events in the pathway leading to error removal and DNA re-synthesis. These actions, enabled by the ATPase activity of MutS, are now beginning to be analyzed from the perspective of the prote...

詳細記述

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書誌詳細
主要な著者: Sharma, Anushi, Doucette, Christopher, Biro, F. Noah, Hingorani, Manju M.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812353/
https://ncbi.nlm.nih.gov/pubmed/23973435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.08.011
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