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Slow conformational changes in MutS and DNA direct ordered transitions between mismatch search, recognition and signaling of DNA repair
MutS functions in mismatch repair (MMR) to scan DNA for errors, identify a target site and trigger subsequent events in the pathway leading to error removal and DNA re-synthesis. These actions, enabled by the ATPase activity of MutS, are now beginning to be analyzed from the perspective of the prote...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812353/ https://ncbi.nlm.nih.gov/pubmed/23973435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.08.011 |
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