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Generation of Guanine -Thymine Crosslinks in Human Cells by One-Electron Oxidation Mechanisms
The one-electron oxidation of cellular DNA in cultured human HeLa cells initiated by intense nanosecond 266 nm laser pulse irradiation produces cross-links between guanine and thymine bases (G*-T*), characterized by a covalent bond between C8 guanine (G*) and N3 thymine (T*) atoms. The DNA lesions w...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812307/ https://ncbi.nlm.nih.gov/pubmed/23734842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400158g |
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