Essential Role of the m(2)R-RGS6-I(KACh) Pathway in Controlling Intrinsic Heart Rate Variability

Normal heart function requires generation of a regular rhythm by sinoatrial pacemaker cells and the alteration of this spontaneous heart rate by the autonomic input to match physiological demand. However, the molecular mechanisms that ensure consistent periodicity of cardiac contractions and fine tu...

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Autori principali: Posokhova, Ekaterina, Ng, David, Opel, Aaisha, Masuho, Ikuo, Tinker, Andrew, Biesecker, Leslie G., Wickman, Kevin, Martemyanov, Kirill A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812209/
https://ncbi.nlm.nih.gov/pubmed/24204714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076973
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