Essential Role of the m(2)R-RGS6-I(KACh) Pathway in Controlling Intrinsic Heart Rate Variability

Normal heart function requires generation of a regular rhythm by sinoatrial pacemaker cells and the alteration of this spontaneous heart rate by the autonomic input to match physiological demand. However, the molecular mechanisms that ensure consistent periodicity of cardiac contractions and fine tu...

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Detalhes bibliográficos
Main Authors: Posokhova, Ekaterina, Ng, David, Opel, Aaisha, Masuho, Ikuo, Tinker, Andrew, Biesecker, Leslie G., Wickman, Kevin, Martemyanov, Kirill A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812209/
https://ncbi.nlm.nih.gov/pubmed/24204714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076973
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