GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes

The extent and temporal characteristics of G protein–coupled receptor (GPCR) signaling are shaped by the regulator of G protein signaling (RGS) proteins, which promote G protein deactivation. With hundreds of GPCRs and dozens of RGS proteins, compartmentalization plays a key role in establishing sig...

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Detalhes bibliográficos
Main Authors: Orlandi, Cesare, Posokhova, Ekaterina, Masuho, Ikuo, Ray, Thomas A., Hasan, Nazarul, Gregg, Ronald G., Martemyanov, Kirill A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373406/
https://ncbi.nlm.nih.gov/pubmed/22689652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201202123
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