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RGS6, but Not RGS4, Is the Dominant Regulator of G Protein Signaling (RGS) Modulator of the Parasympathetic Regulation of Mouse Heart Rate

Parasympathetic activity decreases heart rate (HR) by inhibiting pacemaker cells in the sinoatrial node (SAN). Dysregulation of parasympathetic influence has been linked to sinus node dysfunction and arrhythmia. RGS (regulator of G protein signaling) proteins are negative modulators of the parasympa...

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書誌詳細
主要な著者: Wydeven, Nicole, Posokhova, Ekaterina, Xia, Zhilian, Martemyanov, Kirill A., Wickman, Kevin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900986/
https://ncbi.nlm.nih.gov/pubmed/24318880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520742
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