Clinical Pharmacodynamic Index Identification for Micafungin in Esophageal Candidiasis: Dosing Strategy Optimization

Echinocandins exhibit concentration-dependent effects on Candida species, and preclinical studies support the administration of large, infrequent doses. The current report examines the pharmacokinetics/pharmacodynamics of two multicenter, randomized trials of micafungin dosing regimens that differed...

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Detalhes bibliográficos
Main Authors: Andes, David R., Reynolds, Daniel K., Van Wart, Scott A., Lepak, Alexander J., Kovanda, Laura L., Bhavnani, Sujata M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811328/
https://ncbi.nlm.nih.gov/pubmed/23959319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01057-13
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