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Pharmacodynamic Evaluation of Rezafungin (CD101) against Candida auris in the Neutropenic Mouse Invasive Candidiasis Model

Rezafungin (CD101) is a novel echinocandin under development for once-weekly intravenous (i.v.) dosing. We evaluated the pharmacodynamics (PD) of rezafungin against 4 Candida auris strains, using the neutropenic mouse invasive candidiasis model. The area under the concentration-time curve (AUC)/MIC...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lepak, Alexander J., Zhao, Miao, Andes, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201117/
https://ncbi.nlm.nih.gov/pubmed/30181375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01572-18
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