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Pharmacodynamic Optimization for Treatment of Invasive Candida auris Infection

Candida auris is an emerging multidrug-resistant threat. The pharmacodynamics of three antifungal classes against nine C. auris strains was explored using a murine invasive candidiasis model. The total drug median pharmacodynamic (PD) target associated with net stasis was a fluconazole AUC/MIC (the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lepak, Alexander J., Zhao, Miao, Berkow, Elizabeth L., Lockhart, Shawn R., Andes, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527602/
https://ncbi.nlm.nih.gov/pubmed/28584152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00791-17
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