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Efficacy of Extended-Interval Dosing of Micafungin Evaluated Using a Pharmacokinetic/Pharmacodynamic Study with Humanized Doses in Mice

The pharmacokinetic/pharmacodynamic (PK/PD) characteristics of the echinocandins favor infrequent administration of large doses. The in vivo investigation reported here tested the utility of a range of humanized dose levels of micafungin using a variety of prolonged dosing intervals for the preventi...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Lepak, A., Marchillo, K., VanHecker, J., Azie, N., Andes, D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704180/
https://ncbi.nlm.nih.gov/pubmed/26552968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02124-15
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